L-Tryptophan

L-Tryptophan

Product Name:

L-Tryptophan

Packing:

25kgs/bag

CAS  NO:

73-22-3

Molecular Formula:

C11h12n2o2

Molecular Structure:

Physico-chemical properties:

White Powder

Picture:

L-tryptophan is an amino acid, a protein building block that can be found in many plant and animal proteins. L-tryptophan is called an "essential" amino acid because the body can't make it. It must be acquired from food.
Application

Tryptophan is an essential amino acid which is the precursor of serotonin. Serotonin is a brain neurotransmitter, platelet clotting factor and neurohormone found in organs throughout the body. Metabolism of tryptophan to serotonin requires nutrients such as vitamin B6, niacin and glutathione. Niacin is an important metabolite of tryptophan. High corn or other tryptophan-deficient diets can cause pellagra, which is a niacin-tryptophan deficiency disease with symptoms of dermatitis, diarrhea and dementia. Inborn errors of tryptophan metabolism exist where a tumor (carcinoid) makes excess serotonin. Hartnup's disease is a disease where tryptophan and other amino acids are not absorbed properly.

Tryptophan supplements may be useful in each condition, in carcinoid replacing the over-metabolized nutrient and in Hartnup's supplementing a malabsorbed nutrient. Some disorders of excess tryptophan in the blood may contribute to mental retardation. Assessment of tryptophan deficiency is done through studying excretion of tryptophan metabolites in the urine or blood. Blood may be the most sensitive test because the amino acid tryptophan is transported in a unique way. Increased urination of tryptophan fragments correlates with increased tryptophan degradation, which occurs with oral contraception, depression, mental retardation, hypertension and anxiety states.

The requirement for tryptophan and protein decreases with age. Adults' minimum daily requirement is 3 mg/kg/day or about 200 mg a day. This may be an underestimation, for there are 400 mg of tryptophan in just a cup of wheat germ. A cup of low fat cottage cheese contains 300 mg of tryptophan and chicken and turkey contain up to 600 mg per pound.

L-tryptophan is in plant auxin biosynthesis important precurssubstances, the structure the IAA similar, in higher plant are common. Can through the tryptophan auxin, there are two synthetic ways: (1) tryptophan first oxidation take off ammonia indoles acetone, to form the decarboxylation form indole acetaldehyde; Acetaldehyde in the corresponding of indoles enzyme catalytic oxidation as final indoles acetic acid. (2) tryptophan decarboxylation, which formed first, then by colamine oxidation take off ammonia acid indoles formation.

L-tryptophan is used for insomnia, sleep apnea, depression, anxiety, facial pain, a severe form of premenstrual syndrome called premenstrual dysphoric disorder (PMDD), smoking cessation, grinding teeth during sleep (bruxism), attention deficit-hyperactivity disorder (ADHD), Tourette's syndrome, and to improve athletic performance.

L-Tryptophan

Brand Name

Rongsheng

Specification

99% L-Tryptophan

Appearance

White Crystal Powder

Molecular Formular

C11H12N2O2

Molecular Weight

204.23

Specific rotation

-29.4°~ -32.8°

Assay

99%

PH

5.5-7.0

Heavy metal(Pb)

≤0.0015%

Residue on ignition

≤0.1%

Loss on drying

≤0.3%

Odor

Characteristic

Taste

Characteristic

Sulphate SO42-

≤0.03%

Iron(Fe)

≤0.3%

Chloride(Cl)

≤0.05%

Supplier

Xi'an Rongsheng Biotechnology Co.,Ltd

Package

1kg/bag, 5kg/bag, 25kg/drum

Shelf life

2 years

Storage

Store in cool dry place,avoid sunlight and high temperature.